A National Institutes of Health U01 grant was recently awarded to CAPRISA Research Associate Professor Lynn Morris as part of the H3Africa initiative. This grant aims to examine antibody gene diversity and its impact on neutralizing and non-neutralizing functions. It builds on previous studies by Catherine Scheepers showing a high frequency of novel alleles in the CAPRISA cohort as well as work by Bronwen Lambson and Simone Richardson, at the Nation-al Institutes of Communicable Dis-eases (NICD), on how changes in the Fc region impact effector functions. It is hoped, “that this work will help to better understand the human antibody response to HIV infection and ultimately inform vaccine development,” explained Morris, who is a Research Professor in the Faculty of Health Sciences at the University of Witwatersrand and is the Head of the HIV Virology Laboratory in the Centre for HIV & STIs at the NICD.
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