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Home / Scientific Publications

Scientific Publications

Moving towards universal health coverage: Strengthening the evidence ecosystem for the South African health system
Mathews C, Goga A, Loveday M, Zembe W, Daviaud E, Siegfried N, Lewin S
S Afr Med J. 2019 5;109(11b):8-14.

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Ethical issues associated with HIV phylogenetics in HIV transmission dynamics research: A review of the literature using the Emanuel Framework
Mutenherwa F, Wassenaar DR, de Oliveira T
Dev World Bioeth. 2019;19(1):25-35.

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Antimicrobial stewardship at Prince Mshiyeni Memorial Hospital in KwaZulu-Natal–A pharmacist’s perspective on this multidisciplinary strategy
Ramsamy Y, Steele G, Parbhoo N, Reddy M, Ramjee RJ, Naidoo N, Mhlongo T, Nansook HB
SA Pharmaceutical Journal. 2019 2;86(5):15-6.

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Advancing HIV Vaccine Research With Low-Cost High-Performance Computing Infrastructure: An Alternative Approach for Resource-Limited Settings
Mabvakure BM, Rott R, Dobrowsky L, Van Heusden P, Morris L, Scheepers C, Moore PL
Bioinform Biol Insights 2019; 13:1177932219882347

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Long-term adherence to antiretroviral therapy in a South African adult patient cohort: a retrospective study.
Moosa A, Gengiah TN, Lewis L, Naidoo K.
BMC Infectious Diseases 2019; 19(1):775. doi: 10.1186/s12879-019-4410-8.

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Somatic hypermutation to counter a globally rare viral immunotype drove off-track antibodies in the CAP256-VRC26 HIV-1 V2-directed bNAb lineage.
Sacks D, Bhiman JN, Wiehe K, Gorman J, Kwong PD, Morris L, Moore PL.
PLOS Pathogens 2019; 15(9):e1008005. doi: 10.1371/journal.ppat.1008005.

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Mechanisms of sexually transmitted infection-induced inflammation in women: implications for HIV risk.
Mwatelah R, McKinnon LR, Baxter C, Abdool Karim Q, Abdool Karim SS.
Journal of the International AIDS Society 2019; 22 (Suppl 6):e25346. doi: 10.1002/jia2.25346.

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HPV infection and the genital cytokine milieu in women at high risk of HIV acquisition.
Liebenberg L*, McKinnon L*, Yende-Zuma N*, Garrett N, Baxter C, Kharsany A, Archary D, Rositch A, Samsunder N, Mansoor L, Passmore J-A, Abdool Karim S, Abdool Karim Q.
Nature Communication 2019; 10(1): 522719. doi: 10.1038/s41467-019-13089-2.

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Impact of HIV testing and treatment services on risky sexual behaviour in the uMgungundlovu District, KwaZulu-Natal, South Africa: a cross-sectional study
George G, Beckett S, Cawood C, Khanyile D, Govender K, Kharsany ABM.
AIDS Research and Therapy 2019; 16(1):20. doi: 10.1186/s12981-019-0237-z.

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Contraceptive method switching among women living in sub-Saharan Africa participating in an HIV-1 prevention trial: a prospective cohort study.
Chappell CA, Harkoo I, Szydlo DW, Bunge KE, Singh D, Nakabiito C, Mhlanga F, Kamira B, Piper JM, Balkus JE, Hillier SL.
Contraception 2019; 100(3):214-218.

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Age-disparate partnerships and HSV-2 among adolescent girls and young women in South Africa: implications for HIV infection risk.
Maughan-Brown B, George G, Beckett S, Evans M, Lewis L, Cawood C, Khanyile D, Kharsany ABM.
Sexually Transmitted Infections 2019; 95(6):443-448.

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Ethical challenges in global health-related stigma research.
Millum J, Campbell M, Luna F, Malekzadeh A, Abddol Karim Q.
BMC Medicine 2019; 17(1):84. doi: 10.1186/s12916-019-1317-6.

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Majority of the replication-competent HIV-1 reservoir is established close to the time of treatment initiation
Melissa-Rose Abrahams, Sarah B. Joseph, Nigel Garrett, Lynn Tyers, Matthew Moeser, Nancie Archin, Olivia D. Council, David Matten, Shuntai Zhou, Deelan Doolabh, Colin Anthony, Nilu Goonetilleke, Salim Abdool Karim, David M. Margolis, Sergei Kosakovsky Pond, Carolyn Williamson, Ronald Swanstrom
Science Translational Medicine

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Health and economic burden of influenza-associated illness in South Africa, 2013-2015.
Tempia S, Moyes J, Cohen AL, Walaza S, Edoka I, McMorrow ML, Treurnicht FK, Hellferscee O, Wolter N, von Gottberg A, Nguweneza A, McAnerney JM, Dawood H, Variava E, Cohen C.
Influenza and Other Respiratory Viruses 2019;13(5):484-495.

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Partner HIV serostatus impacts viral load, genital HIV shedding and immune activation in HIV-infected individuals.
Jaumdally SZ, Liebenberg LJP, Gumbi PP, Little F, Jaspan HB, Gamieldien H, Tiemessen CT, Coetzee D, Martin DP, Williamson C, Williamson AL, Passmore JS.
JAIDS 2019; 82(1):51-60.

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A mucosal barrier for topical HIV PrEP?
Masson L, McKinnon LR.
Lancet HIV 2019; 6(8):e484-e485. doi: 10.1016/S2352-3018(19)30187-0.

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Asymptomatic bacterial vaginosis in pregnancy and missed opportunities for treatment: a cross-sectional observational study.
Joyisa N, Moodley D, Nkosi T, Talakgale R, Sebitloane M, Naidoo M, Abdool Karim Q.
Infectious Diseases in Obstetrics and Gynecology 2019; 2019:7808179. doi: 10.1155/2019/7808179.

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High rate of occult hepatitis B virus infection in haemodialysis units of KwaZulu-Natal, South Africa.
Msomi N, Ndlovu K, Giandhari J, Wilkinson E, Parboosing R, Zungu S, Mlisana K.
Journal of Medical Virology 2019; 91(10):1797-1803.

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Healthcare utilisation patterns for respiratory and gastrointestinal syndromes and meningitis in Msunduzi municipality, Pietermaritzburg, KwaZulu-Natal Province, South Africa, 2013.
McAnerney JM, Cohen C, Cohen AL, Tempia S, Walaza S, Wong KK, Im J, Marks F, Dawood H, Panzner U, Keddy KH, Von Mollendorf C.
South African Medical Journal 2019; 109(5):333-339.

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Predicting the risk of pulmonary tuberculosis based on the neutrophil-to-lymphocyte ratio at TB screening in HIV-infected individuals.
Miyahara R, Piyaworawong S, Naranbhai V, Prachamat P, Kriengwatanapong P, Tsuchiya N, Wongyai J, Bupachat S, Yamada N, Summanapan S, Mahasirimongkol S, Yanai H.
BMC Infectious Diseases 2019; 19(1):667. doi: 10.1186/s12879-019-4292-9.

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AAV-Mediated Expression of Broadly Neutralizing and Vaccine-like Antibodies Targeting the HIV-1 Envelope V2 Region.
van den Berg FT, Makoah NA, Ali SA, Scott TA, Mapengo RE, Mutsvunguma LZ, Mkhize NN, Lambson BE, Kgagudi PD, Crowther C, Abdool Karim SS, Balazs AB, Weinberg MS, Ely A, Arbuthnot PB, Morris L.
Molecular Therapy: Methods & Clinical Development 2019; 14:100-112.

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Plasma IL-5 but not CXCL13 correlates with neutralization breadth in HIV-infected children.
Roider J, Porterfield JZ, Ogongo P, Muenchhoff M, Adland E, Groll A, Morris L, Moore PL, Ndung'u T, Kløverpris H, Goulder PJR, Leslie A.
Frontiers in Immunology 2019; 10:1497. doi: 10.3389/fimmu.2019.01497.

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Space-time clustering of recently-diagnosed tuberculosis and impact of ART scale-up: Evidence from an HIV hyper-endemic rural South African population.
Tomita A, Smith CM, Lessells RJ, Pym A, Grant AD, de Oliveira T, Tanser F.
Scientific Reports 2019; 9(1):10724. doi: 10.1038/s41598-019-46455-7.

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Informed consent and community engagement in open field research: lessons for gene drive science.
Singh JA.
BMC Medical Ethics 2019; 20(1):54. doi: 10.1186/s12910-019-0389-3.

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Exploring factors that influence the integration of HIVST with HCT using a qualitative comparative cross-over design in KwaZulu-Natal, South Africa.
Harichund C, Abdool Karim Q, Kunene P, Simelane S, Moshabela M.
Glob Public Health 2019;14(9):1275-1287.

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Home-based intervention to test and start (HITS) protocol: a cluster-randomized controlled trial to reduce HIV-related mortality in men and HIV incidence in women through increased coverage of HIV treatment.
Mathenjwa T, Kim HY, Zuma T, Shahmanesh M, Seeley J, Matthews P, Wyke S, McGrath N, Sartorius B, Yapa HM, Adeagbo O, Blandford A, Dobra A, Bäernighausen T, Tanser F.
BMC Public Health 2019; 19(1):969.

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Rapid and Focused Maturation of a VRC01-Class HIV Broadly Neutralizing Antibody Lineage Involves Both Binding and Accommodation of the N276-Glycan.
Umotoy J, Bagaya BS, Joyce C, Schiffner T, Menis S, Saye-Francisco KL, Biddle T, Mohan S, Vollbrecht T, Kalyuzhniy O, Madzorera S, Kitchin D, Lambson B, Nonyane M, Kilembe W; IAVI Protocol C Investigators; IAVI African HIV Research Network, Poignard P, Schief WR, Burton DR, Murrell B, Moore PL, Briney B, Sok D, Landais E.
Immunity 2019; 51(1):141-154.

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Risk of HIV-1 acquisition among South African women using a variety of contraceptive methods in a prospective study.
Palanee-Phillips T, Brown ER, Szydlo D, Matovu Kiweewa F, Pather A, Harkoo I, Nair G, Soto-Torres L, Hillier SL, Baeten JM; MTN-020/ASPIRE Study Team.
AIDS 2019; 33(10):1619-1622.

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Outcomes of Stevens-Johnson syndrome and toxic epidermal necrolysis in HIV-infected patients when using systemic steroids and/or intravenous immunoglobulins in Pietermaritzburg, South Africa.
Chateau AV, Dlova NC, Dawood H, Aldous C.
Southern African Journal of HIV Medicine 2019; 20(1):944. doi: 10.4102/sajhivmed.v20i1.944.

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Feasibility of HIV self-testing: experiences of people seeking HIV testing in rural and urban KwaZulu-Natal, South Africa.
Harichund C, Kunene P, Moshabela M.
African Journal of AIDS Research 2019; 18(2):115-122.

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Frequency of Hepatitis B Virus Resistance Mutations in Women Using Tenofovir Gel as Pre-Exposure Prophylaxis.
Baxter C, Ngcapu S, Blackard JT, Powell EA, Penton PK, Abdool Karim SS.
Viruses 2019; 11(6):E569. doi: 10.3390/v11060569

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Assessing the safety and pharmacokinetics of the monoclonal antibodies, VRC07-523LS and PGT121 in HIV negative women in South Africa: study protocol for the CAPRISA 012A randomised controlled phase I trial.
Mahomed S, Garrett N, Capparelli E, Baxter C, Yende-Zuma N, Gengiah T, Archary D, Moore P, Samsunder N, Barouch DH, Mascola J, Ledgerwood J, Morris L, Abdool Karim SS.
BMJ Open 2019; 9(7):e030283. doi: 10.1136/bmjopen-2019-030283

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TRAV1-2(+) CD8(+) T-cells including oligoconal expansions of MAIT cells are enriched in the airways in human tuberculosis.
Wong EB, Gold MC, Meermeier EW, Xulu BZ, Khuzwayo S, Sullivan ZA, Mahyari E, Rogers Z, Kloverpris H, Sharma PK, Worley AH, Lalloo U, Baijnath P, Ambaram A, Naidoo L, Suleman M, Madansein R, McLaren JE, Ladell K, Miners KL, Price DA, Behar SM, Nielsen M, Kasprowicz VO, Leslie A, Bishai WR, Ndung'u T, Lewinsohn DM.
Communications Biology 2019; 2:203. doi: 10.1038/s42003-019-0442-2.

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Seroprevalence of hepatitis B virus: findings from a population-based household survey in KwaZulu Natal, South Africa.
Samsunder N, Ngcapu S, Lewis L, Baxter C, Cawood C, Khanyile D, Kharsany ABM.
International Journal of Infectious Diseases 2019; 85:150-157.

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Detection of tuberculosis recurrence, diagnosis and treatment response by a blood transcriptomic risk signature in HIV-infected persons on antiretroviral therapy.
Darboe F, Mbandi SK, Naidoo K, Yende-Zuma N, Lewis L, Thompson E, Duffy F, Fisher M, Filander E, van Rooyen M, Bilek N, Mabwe S, McKinnon L, Chegou NN, Loxton AG, Walzl G, Tromp G, Padayatchi N, Govender D, Hatherill M, Abdool Karim SS, Zak D, Penn-Nicholson A, Scriba T.
Frontiers in Microbiology 2019; 10:1441. doi: 10.3389/fmicb.2019.01441.

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Diminished HIV infection of target CD4+ T cells in a Toll-Like Receptor 4 stimulated in vitro model.
Cromarty R, Sigal A, Liebenberg LJ, McKinnon LR, Abdool Karim SS, Passmore JS, Archary D.
Frontiers in Immunology 2019; 10:1705. doi: 10.3389/fimmu.2019.01705.

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Does voluntary medical male circumcision protect against sexually transmitted infections among men and women in real-world scale-up settings? Findings of a household survey in KwaZulu-Natal, South Africa.
Davis S, Toledo C, Lewis L, Maughan-Brown B, Ayalew K, Kharsany ABM.
BMJ Global Health 2019; 4(3):e001389.

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Mapping HIV prevalence in sub-Saharan Africa between 2000 and 2017.
Dwyer-Lindgren L, Cork MA, Sligar A, Steuben KM, Wilson KF, Provost NR, Mayala BK, VanderHeide JD, Collison ML, Hall JB, Biehl MH, Carter A, Frank T, Douwes-Schultz D, Burstein R, Casey DC, Deshpande A, Earl L, El Bcheraoui C, Farag TH, Henry NJ, Kinyoki D, Marczak LB, Nixon MR, Osgood-Zimmerman A, Pigott D, Reiner RC, Ross JM, Schaeffer LE, Smith DL, Davis Weaver N, Wiens KE, Eaton JW, Justman JE, Opio A, Sartorius B, Tanser F, Wabiri N, Piot P, Murray CJL, Hay SI.
Nature 2019; 570(7760):189-193.

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A method for statistical analysis of repeated residential movements to link human mobility and HIV acquisition.
Dobra A, Bärnighausen T, Vandormael A, Tanser F.
PloS One 2019; 14(6):e0217284.

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A decade of sustained geographic spread of HIV infections among women in Durban, South Africa.
Ramjee G, Sartorius B, Morris N, Wand H, Reddy T, Yssel JD, Tanser F.
BMC Infectious Diseases 2019; 19(1):500.

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The antibody response in HIV-1-infected donors.
Richardson SI, Moore PL.
Current Opinion in HIV and AIDS 2019; 14(4):233-239.

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The genital tract and rectal microbiomes: their role in HIV susceptibility and prevention in women.
Abdool Karim SS, Baxter C, Passmore JS, McKinnon LR, Williams BL.
Journal of the International AIDS Society 2019; 22(5):e25300.

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An evaluation to determine the strongest CD4 count covariates during HIV disease progression in women in South Africa.
Tinarwo P, Zewotir T, Yende-Zuma N, Garrett NJ, North D.
Infectious Diseases and Therapy 2019; 8(2):269-284.

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Effects of Migration on Risky Sexual Behavior and HIV Acquisition in South Africa: A Systematic Review and Meta-analysis, 2000-2017.
Dzomba A, Tomita A, Govender K, Tanser F.
AIDS and Behavior 2019; 23(6):1396-1430.

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HIV-1 Epidemic Control-Insights from Test-and-Treat Trials.
Abdool Karim SS.
New England Journal of Medicine 2019; 381(3):286-288.

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Eligibility for co-trimoxazole prophylaxis among adult HIV-infected patients in South Africa.
Takuva S, Nabyoma JM, Dawood H, Black A, Maartens G, Parrish A, Leong TD.
South African Medical Journal 2019; 109(4):198-199.

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Point-of-care HIV viral load testing: an essential tool for a sustainable global HIV/AIDS response.
Drain PK, Dorward J, Bender A, Lillis L, Marinucci F, Sacks J, Bershteyn A, Boyle DS, Posner JD, Garrett N.
Clinical Microbiology Reviews 2019; 32(3): e00097-18.

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Can community pharmacists improve tuberculosis case finding? A mixed methods intervention study in India.
Daftary A, Satyanarayana S, Jha N, Singh M, Mondal S, Vadnais C, Pai M.
BMJ Global Health 2019; 4(3):e001417. doi:10.1136/bmjgh-2019-001417

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Evidence for both intermittent and persistent compartmentalization of HIV-1 in the female genital tract.
Mabvakure BM, Lambson BE, Ramdayal K, Masson L, Kitchin D, Allam M, Abdool Karim SS, Williamson C, Passmore J, Martin DP, Scheepers C, Moore PL, Harkins GW, Morris L.
Journal of Virology 2019; 93(10):e00311-19. doi: 10.1128/JVI.00311-19.

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Trends in pretreatment HIV-1 drug resistance in antiretroviral therapy-naive adults in South Africa, 2000–2016: a pooled sequence analysis.
Chimukangara B, Lessells RJ, Rhee S-Y, Giandhari J, Kharsany ABM, Naidoo K, Lewis L, Cawood C, Khanyile D, Ayalew KA, Diallo K, Samuel R, Hunt G, Vandormael A, Stray-Pedersen B, Gordon M, Makadzange T, Kiepiela P, Ramjee G, Ledwaba J, Kalimashe M, Morris L, Parikh UM, Mellors JW, Shafer RW, Katzenstein D, Moodley P, Gupta RK, Pillay D, Abdool Karim SS, de Oliveira T.
EClinicalMedicine 2019; 9:26-34.

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rpoB Mutations Causing Discordant Rifampicin Susceptibility in Mycobacterium tuberculosis: Retrospective Analysis of Prevalence, Phenotypic, Genotypic, and Treatment Outcomes.
Mvelase NR, Pillay M, Sibanda W, Ngozo JN, Brust JCM, Mlisana KP.
Open Forum Infectious Diseases provides 2019; 6(4):ofz065. doi: 10.1093/ofid/ofz065.

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Remembering the Host in Tuberculosis Drug Development.
Frank DJ, Horne DJ, Dutta NK, Shaku MT, Madensein R, Hawn TR, Steyn AJC, Karakousis PC, Kana BD, Meintjes G, Laughon B, Tanvir Z.
Journal of Infectious Diseases 2019; 219(10):1518-24.

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Rational design and in vivo selection of SHIVs encoding transmitted/founder subtype C HIV-1 envelopes.
O'Brien SP, Swanstrom AE, Pegu A, Ko SY, Immonen TT, Del Prete GQ, Fennessey CM, Gorman J, Foulds KE, Schmidt SD, Doria-Rose N, Williamson C, Hatziioannou T, Bieniasz PD, Li H, Shaw GM, Mascola JR, Koup RA, Kwong PD, Lifson JD, Roederer M, Keele BF.
PloS Pathogens 2019; 15(4):e1007632.

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Defining characteristics of genital health in South African adolescent girls and young women at high risk for HIV infection.
Dabee S, Barnabas SL, Lennard KS, Jaumdally SZ, Gamieldien H, Balle C, Happel AU, Murugan BD, Williamson AL, Mkhize N, Dietrich J, Lewis DA, Chiodi F, Hope TJ, Shattock R, Gray G, Bekker LG, Jaspan HB, Passmore JS.
PloS One 2019; 14(4):e0213975. doi: 10.1371/journal.pone.0213975.

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The STREAM trial: missed opportunities and lessons for future clinical trials.
Loveday M, Reuter A, Furin J, Seddon JA, Cox H.
Lancet Infectious Diseases 2019; 19(4):351-353.

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Prime-boost immunizations with DNA, Modified Vaccinia Virus Ankara, and protein-based vaccines elicit robust HIV-1 Tier 2 neutralizing antibodies against the CAP256 superinfecting virus.
van Diepen MT, Chapman R, Douglass N, Galant S, Moore PL, Margolin E, Margolin E, Ximba P, Morris L, Rybicki EP, Williamson AL.
Journal of Virology 2019; 93(8): e02155-18. doi: 10.1128/JVI.02155-18.

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Effects of genetic variability on rifampicin and isoniazid pharmacokinetics in South African patients with recurrent tuberculosis.
Naidoo A, Chirehwa M, Ramsuran V, McIlleron H, Naidoo K, Yende-Zuma N, Singh R, Ncgapu S, Adamson J, Govender K, Denti P, Padayatchi N.
Pharmacogenomics 2019; 20(4):225-240.

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Immunoscreening of the M. tuberculosis F15/LAM4/KZN secretome library against TB patients' sera identifies unique active- and latent-TB specific biomarkers.
Chiliza TE, Pillay M, Naidoo K, Pillay B.
Tuberculosis 2019; 115:161-170.

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Major depression and household food insecurity among individuals with multidrug-resistant tuberculosis (MDR-TB) in South Africa.
Tomita A, Ramlall S, Naidu T, Mthembu SS, Padayatchi N, Burns JK.
Social Psychiatry and Psychiatric Epidemiology 2019; 54(3):387-393.

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Early detection of emergent extensively drug resistant tuberculosis (XDR-TB) by flow cytometry-based phenotyping and whole genome sequencing.
O'Donnell MR, Larsen MH, Brown TS, Jain P, Munsamy V, Wolf A, Uccellini L, Karim F, D'Olivera T, Mathema B, Jacobs WR, Pym A.
Antimicrobial Agents Chemotherapy 2019; 63(4): e01834-18. doi: 10.1128/AAC.01834-18.

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Challenges and clinical relevance of molecular detection of Bordetella pertussis in South Africa.
Moosa F, du Plessis M, Wolter N, Carrim M, Cohen C, von Mollendorf C, Walaza S, Tempia S, Dawood H, Variava E, von Gottberg A.
BMC Infectious Diseases 2019; 19(1):276. doi: 10.1186/s12879-019-3869-7.

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World Health Organization Guidance on Ethical Considerations in Planning and Reviewing Research Studies on Sexual and Reproductive Health in Adolescents.
Singh JA, Siddiqi M, Parameshwar P, Chandra-Mouli V.
Journal of Adolescent Health 2019; 64(4):427-429

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Who is sexually active? Using a multi-component sexual activity profile (MSAP) to explore, identify and describe sexually-active high-school students in rural KwaZulu-Natal, South Africa.
Humphries H, Osman F, Knight L, Abdool Karim Q.
BMC Public Health 2019; 19(1):317. doi: 10.1186/s12889-019-6602-y.

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Characterization of putative DD-carboxypeptidase-encoding genes in Mycobacterium smegmatis.
Ealand CS, Asmal R, Mashigo L, Campbell L, Kana BD.
Scientific Reports 2019; 9(1):5194. doi: 10.1038/s41598-019-41001-x.

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Neurocognitive Impairment Risk Among Individuals With Multiple Drug-Resistant Tuberculosis and Human Immunodeficiency Virus Coinfection: Implications for Systematic Linkage to and Retention of Care in Tuberculosis/Human Immunodeficiency Virus Treatment.
Tomita A, Ramlall S, Naidu T, Mthembu SS, Padayatchi N, Burns JK.
Journal of Nervous and Mental Disease 2019; 207(4):307-310.

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Precision Medicine in Resistant Tuberculosis: Treat the correct patient, at the correct time, with the correct drug.
Mahomed S, Padayatchi N, Singh J, Naidoo K. doi: 10.1016/j.jinf.2019.03.006.
Journal of Infection 2019; 78(4): 261-268.

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Semen IgM, IgG1, and IgG3 Differentially Associate With Pro-Inflammatory Cytokines in HIV-Infected Men.
Pillay T, Sobia P, Olivier AJ, Narain K, Liebenberg LJP, Ngcapu S, Mhlongo M, Passmore JS, Baxter C, Archary D.
Frontiers in immunology 2019; 9:3141. doi: 10.3389/fimmu.2018.03141.

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Coital frequency and condom use in age-disparate partnerships involving women aged 15 to 24: evidence from a cross-sectional study in KwaZulu-Natal, South Africa.
George G, Maughan-Brown B, Beckett S, Evans M, Cawood C, Khanyile D, Govender K, Kharsany AB.
BMJ Open 2019; 9(3):e024362. doi: 10.1136/bmjopen-2018-024362.

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Critical issues for research in diagnostics and therapeutics for tuberculosis infection.
Keshavjee S, Amanullah F, Cattamanchi A, Chaisson R, Dobos KM, Fox GJ, Gendelman HE, Gordon R, Hesseling A, Le Van H, Kampmann B, Kana B, Khuller G, Lewinsohn DM, Lewinsohn DA, Lin PL, Lu LL, Maartens G, Owen A, Protopopova M, Rengarajan J, Rubin E, Salgame P, Schurr E, Seddon JA, Swindells S, Tobin DM, Udwadia Z, Walzl G, Srinivasan S, Rustomjee R, Nahid P. Moving toward tuberculosis elimination.
American Journal of Respiratory and Critical Care Medicine 2019; 199(5):564-571.

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The evolving facets of bacterial vaginosis: implications for HIV transmission.
McKinnon LR, Achilles S, Bradshaw CS, Burgener A, Crucitti T, Fredricks DN, Jaspan HB, Kaul R, Kaushic C, Klatt N, Kwon DS, Marrazzo JM, Masson L, McClelland S, Ravel J, van de Wijgert JHHM, Vodstrcil LA, Tachedjian G.
AIDS Research and Human Retroviruses 2019; 35(3):219-228.

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Positive selection at key residues in the HIV Envelope distinguishes broad and strain-specific plasma neutralizing antibodies.
Mabvakure BM, Scheepers C, Garrett N, Abdool Karim S, Williamson C, Morris L, Moore PL.
Journal of Virology 2019; 93(6): e01685-18. doi: 10.1128/JVI.01685-18.

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Experts' Perspectives on Key Ethical Issues Associated With HIV Phylogenetics as Applied in HIV Transmission Dynamics Research.
Mutenherwa F, Wassenaar DR, de Oliveira T.
Journal of Empirical Research on Human Research Ethics 2019; 14(1):61-77.

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Transmission of drug-resistant tuberculosis in HIV-endemic settings.
Khan PY, Yates TA, Osman M, Warren RM, van der Heijden Y, Padayatchi N, Nardell EA, Moore D, Mathema B, Gandhi N, Eldholm V, Dheda K, Hesseling AC, Mizrahi V, Rustomjee R, Pym A.
Lancet Infectious Disease 2019; 19(3):e77-e88.

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Advances in the understanding of Mycobacterium tuberculosis transmission in HIV-endemic settings.
Peters JS, Andrews JR, Hatherill M, Hermans S, Martinez L, Schurr E, van der Heijden Y, Wood R, Rustomjee R, Kana BD.
Lancet Infectious Disease 2019; 19(3):e65-e76.

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Repeat HIV testing practices in the era of HIV self-testing among adults in KwaZulu-Natal, South Africa.
Harichund C, Kunene P, Simelane S, Abdool Karim Q, Moshabela M.
PLoS One 2019; 14(2):e0212343.

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Antimicrobial and inflammatory properties of South African clinical Lactobacillus isolates and vaginal probiotics.
Chetwin E, Manhanzva MT, Abrahams AG, Froissart R, Gamieldien H, Jaspan H, Jaumdally SZ, Barnabas SL, Dabee S, Happel AU, Bowers D, Davids L, Passmore JS, Masson L.
Scientific reports 2019; 9(1):1917.

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Effect of ART scale-up and female migration intensity on risk of HIV acquisition: results from a population-based cohort in KwaZulu-Natal, South Africa.
Dzomba A, Tomita A, Vandormael A, Govender K, Tanser F.
BMC Public Health 2019; 19(1):196.

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Sociobehavioral and community predictors of unsuppressed HIV viral load: multilevel results from a hyperendemic rural South African population.
Tomita A, Vandormael A, Bärnighausen T, Phillips A, Pillay D, De Oliveira T, Tanser F.
AIDS 2019; 33(3):559-569.

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Antiretroviral switching and bedaquiline treatment of drug-resistant tuberculosis HIV co-infection.
O'Donnell MR, Padayatchi N, Daftary A, Orrell C, Dooley KE, Rivet Amico K, Friedland G.
Lancet HIV 2019; 6(3):e201-e204.

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Adjusting the Effect of Integrating Antiretroviral Therapy and Tuberculosis Treatment on Mortality for Noncompliance: A Time-varying Instrumental Variables Analysis.
Yende-Zuma N, Mwambi H, Vansteelandt S.
Epidemiology 2019; 30(2):197-203.

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Dolutegravir in sub-Saharan Africa: context is crucial.
Dorward J, Hamers RL.
Lancet HIV 2019; 6(2):e72-e73.

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Moderate-to-High Levels of Pretreatment HIV Drug Resistance in KwaZulu-Natal Province, South Africa.
Chimukangara B, Kharsany AB, Lessells RJ, Naidoo K, Rhee SY, Manasa J, Gräf T, Lewis L, Cawood C, Khanyile D, Diallo K, Ayalew KA, Shafer R, Hunt G, Pillay D, Abdool Karim SS, de Oliveira T.
AIDS Research and Human Retroviruses 2019; 35(2):129-138.

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Diagnostic accuracy of the Xpert CT/NG and OSOM Trichomonas Rapid assays for point-of-care STI testing among young women in South Africa: a cross-sectional study.
Garrett N, Mitchev N, Osman F, Naidoo J, Dorward J, Singh R, Ngobese H, Rompalo A, Mlisana K, Mindel A.
BMJ Open 2019; 9(2):e026888.

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Tuberculosis: treatment failure, or failure to treat? Lessons from India and South Africa.
Padayatchi N, Daftary A, Naidu N, Naidoo K, Pai M.
BMJ Global Health 2019; 4(1):e001097. doi:10.1136/bmjgh-2018-001097.

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Inflammatory cytokine biomarkers of asymptomatic sexually transmitted infections and vaginal dysbiosis: a multicentre validation study.
Masson L, Barnabas S, Deese J, Lennard K, Dabee S, Gamieldien H, Jaumdally SZ, Williamson AL, Little F, Van Damme L, Ahmed K, Crucitti T, Abdellati S, Bekker LG, Gray G, Dietrich J, Jaspan H, Passmore JS.
Sexually Transmitted Infections 2019; 95(1):5-12.

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The impact of home-based HIV testing services on progress towards the UNAIDS 90-90-90 targets in a hyperendemic area of South Africa.
Lewis L, Maughan-Brown B, Grobler A, Cawood C, Khanyile D, Glenshaw M, Kharsany ABM.
J Acquir Immune Defic Syndr. 2019; 80(2):135-144.

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HIV self-testing as part of a differentiated HIV testing approach: exploring urban and rural adult experiences from KwaZulu-Natal, South Africa using a cross-over study design.
Harichund C, Abdool Karim Q, Kunene P, Simelane S, Moshabela M.
BMC Public Health 2019; 19(1):53. doi: 10.1186/s12889-018-6366-9.

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Interventions to improve retention-in-care and treatment adherence among patients with drug-resistant tuberculosis: a systematic review.
Law S, Daftary A, O'Donnell M, Padayatchi N, Calzavara L, Menzies D.
European Respiratory Journal 2019; 53(1):1801030. doi: 10.1183/13993003.01030-2018.

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Pre-eclampsia: the role of highly active antiretroviral therapy and immune markers.
Phoswa WN, Naicker T, Ramsuran V, Moodley J.
Inflammation Research 2019; 68(1):47-57.

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Acceptability of HIV self-testing among men and women in KwaZulu-Natal, South Africa.
Harichund C, Moshabela M, Kunene P, Abdool Karim Q.
AIDS Care 2019; 31(2):186-192.

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'You'll always stay right': understanding vaginal products and the motivations for use among adolescent and young women in rural KZN.
Humphries H, Mehou-Loko C, Phakathi S, Mdladla M, Fynn L, Knight L, Abdool Karim Q.
Culture, Health & Sexuality 2019; 21(1):95-107.

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